Nanoimprinted arrays of glassy carbon nanoelectrodes for improved electrochemistry of enzymatic redox-mediators

In the present study, preparation and electrochemical application of perfectly ordered arrays glassy carbon nanoelectrodes (GC-NEAs) is presented. After careful morphological characterization, we examined voltammetric behaviour on GC-NEAs some redox mediators commonly used in enzymatic biosensors. were fabricated by using nanoimprint lithography to generate nanoholes, with average radius 145 nm, onto a polycarbonate thin film deposited plate. The (ferrocenylmethyl)trimethylammonium (FA+) as typical mediator for oxidase enzymes Azure A B examples reductase enzymes. signals recorded indicate that here prepared operate under total overlap diffusion conditions, an accessible potential window significantly wider than one gold nanoelectrodes. Interestingly, fits what expected basis geometrical features array demonstrating role these parameters ruling contribution capacitive faradic currents which reflect improved detection capabilities.